abstract：:Trypanosomes are parasitic protozoa in which gene expression is primarily controlled through the regulation of mRNA stability and translation. This post-transcriptional control is mediated by various families of RNA-binding proteins, including those with zinc finger CCCH motifs. CCCH zinc finger proteins have been sho...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mörking PA,Rampazzo Rde C,Walrad P,Probst CM,Soares MJ,Gradia DF,Pavoni DP,Krieger MA,Matthews K,Goldenberg S,Fragoso SP,Dallagiovanna B

更新日期：2012-09-01 00:00:00

abstract：:An increased plasma concentration of von Willebrand factor (vWF) is detected in individuals with many infectious diseases and is accepted as a marker of endothelium activation and prothrombotic condition. To determine whether ExoU, a Pseudomonas aeruginosa cytotoxin with proinflammatory activity, enhances the release ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Freitas C,Assis MC,Saliba AM,Morandi VM,Figueiredo CC,Pereira M,Plotkowski MC

更新日期：2012-09-01 00:00:00

abstract：:The hepatitis C virus (HCV) can be detected in blood and other bodily fluids, such as saliva, semen and gastric juices. The aim of this study was to compare the HCV viral loads in the serum and saliva of infected patients. Twenty-nine patients with detectable HCV RNA in their serum and saliva were included in this stu...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Menezes GB,Pereira FA,Duarte CA,Carmo TM,Silva Filho HP,Zarife MA,Krieger MA,Reis EA,Reis MG

更新日期：2012-08-01 00:00:00

abstract：:The aim of the present study was to examine the parasite fauna present in rodent coprolites collected from Cueva Huenul 1 (CH1), northern Neuquén (Patagonia, Argentina), an archaeological site that provides stratified sequences of archaeological and palaeontological remains dating from the Late Pleistocene/Early Holoc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Beltrame MO,Sardella NH,Fugassa MH,Barberena R

更新日期：2012-08-01 00:00:00

abstract：:St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) present ecological and antigenic similarities and are responsible for serious human diseases. In addition, WNV is a significant pathogen in terms of equine health. The purpose of our study was to analyse the seroprevalence of SLEV and WNV in equine sera col...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tauro L,Marino B,Diaz LA,Lucca E,Gallozo D,Spinsanti L,Contigiani M

更新日期：2012-06-01 00:00:00

abstract：:Ascorbate peroxidases (APX) are class I heme-containing enzymes that convert hydrogen peroxide into water molecules. The gene encoding APX has been characterized in 11 strains of Trypanosoma cruzi that are sensitive or resistant to benznidazole (BZ). Bioinformatic analysis revealed the presence of two complete copies ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nogueira FB,Rodrigues JF,Correa MM,Ruiz JC,Romanha AJ,Murta SM

更新日期：2012-06-01 00:00:00

abstract：:In Brazil, carbapenem-resistant Pseudomonas aeruginosa isolates are closely related to the São Paulo metallo-β-lactamase (SPM) Brazilian clone. In this study, imipenem-resistant isolates were divided in two sets, 2002/2003 and 2008/2009, analysed by pulsed field gel electrophoresis and tested for the Ambler class B me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cavalcanti FL,Almeida AC,Vilela MA,Morais MM,Morais Junior MA

更新日期：2012-05-01 00:00:00

abstract：:We investigated the cytokine profile of peripheral mononuclear cells from chronic osteomyelitis (OST) patients following in vitro stimulation with staphylococcal enterotoxin A (SEA). We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-α, i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira GF,Moraes C,Silveira AM,Correa-Oliveira R,Teixeira-Carvalho A,Martins-Filho OA,Moreno EC,do Carmo LS,Fraga LA,Malaquias LC

更新日期：2012-05-01 00:00:00

abstract：:Aedes albopictus was found in six of the 10 departments of Haiti and in 14 of the 35 communes surveyed. The survey found the larvae of Ae. albopictus in 13 different types of containers. Used tires and tins were by far the most common breeding sites used by this mosquito species. At the breeding sites, Ae. albopictus ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fernández Mdel C,Jean YS,Callaba CA,López LS

更新日期：2012-03-01 00:00:00

abstract：:Trypanosoma cruzi infection has a large public health impact in Latin American countries. Although the transmission rates via blood transfusions and insect vectors have declined sharply in the past 20 years due to policies of the Southern Cone countries, a large number of people are still at risk for infection. Curren...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva DR,Castro SL,Alves MC,Batista Wda S,Oliveira GM

更新日期：2012-03-01 00:00:00

abstract：:In this study we compared two polymerase chain reaction (PCR) methods using either 16S ribosomal RNA (rRNA) or 23S rRNA gene primers for the detection of different Leptospira interrogans serovars. The performance of these two methods was assessed using DNA extracted from bovine tissues previously inoculated with sever...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： D'Andrea A,Martinez YZ,Alduina R,Monteverde V,Molina CF,Vitale M

更新日期：2012-02-01 00:00:00

abstract：:Within the country of Brazil, Santa Catarina is a major shellfish producer. Detection of viral contamination is an important step to ensure production quality and consumer safety during this process. In this study, we used a depuration system and ultraviolet (UV) disinfection to eliminate viral pathogens from artifici...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Corrêa Ade A,Rigotto C,Moresco V,Kleemann CR,Teixeira AL,Poli CR,Simões CM,Barardi CR

更新日期：2012-02-01 00:00:00

abstract：:The number of visceral leishmaniasis (VL) cases has increased over the past 10 years in Brazil, especially in the North and Northeast regions of the country. The aim of this study was to evaluate the urbanisation of VL vectors in Barcarena, Pará, an area in northern Brazil where VL is endemic. Sandflies were captured ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira DM,Saraiva EM,Ishikawa EA,Sousa AA,Silva EO,Silva IM

更新日期：2011-12-01 00:00:00

abstract：:Virulence and antibiotic resistance are significant determinants of the types of infections caused by Staphylococcus aureus and paediatric groups remain among the most commonly affected populations. The goal of this study was to characterise virulence genes of methicillin-susceptible S. aureus (MSSA) and methicillin-r...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jiménez JN,Ocampo AM,Vanegas JM,Rodríguez EA,Garcés CG,Patiño LA,Ospina S,Correa MM

更新日期：2011-12-01 00:00:00

abstract：:India was affected by a major outbreak of chikungunya fever caused by Chikungunya virus (CHIKV) during 2006-2007. Kerala was the worst affected state during 2007 with a contribution of 55.8% suspected cases in the country. However, except for clinically reported case records, no systematic information is available on ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kumar NP,Suresh A,Vanamail P,Sabesan S,Krishnamoorthy KG,Mathew J,Jose VT,Jambulingam P

更新日期：2011-12-01 00:00:00

abstract：:Schistosoma mansoni is one of the three main causative agents of human schistosomiasis, a major health problem with a vast socio-economic impact. Recent advances in the proteomic analysis of schistosomes have revealed that peptidases are the main virulence factors involved in the pathogenesis of this disease. In this ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva LL,Marcet-Houben M,Zerlotini A,Gabaldón T,Oliveira G,Nahum LA

更新日期：2011-11-01 00:00:00

abstract：:Only one drug is currently available for the treatment and control of schistosomiasis and the increasing risk of selecting strains of schistosome that are resistant to praziquantel means that the development of new drugs is urgent. With this objective we have chosen to target the enzymes modifying histones and in part...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pierce RJ,Dubois-Abdesselem F,Caby S,Trolet J,Lancelot J,Oger F,Bertheaume N,Roger E

更新日期：2011-11-01 00:00:00

abstract：:The insect fat body plays major roles in the intermediary metabolism, in the storage and transport of haemolymph compounds and in the innate immunity. Here, the overall structure of the fat body of five species of mosquitoes (Aedes albopictus, Aedes fluviatilis, Culex quinquefasciatus, Anopheles aquasalis and Anophele...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martins GF,Serrão JE,Ramalho-Ortigão JM,Pimenta PF

更新日期：2011-09-01 00:00:00

abstract：:The family Nematotaeniidae, tapeworms commonly found in the small intestines of amphibians and reptiles, includes 27 recognised species distributed among four genera: Bitegmen Jones, Cylindrotaenia Jewell, Distoichometra Dickey and Nematotaenia Lühe. The taxonomy of these cestodes is poorly defined, due in part to the...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Melo FT,Giese EG,Furtado AP,Soares MJ,Gonçalves EC,Vallinoto AC,Santos JN

更新日期：2011-09-01 00:00:00

abstract：:In Brazil, malaria still remains a clinically important febrile syndrome for local populations and travelers, occurring mostly in the Amazon Basin. This review aims to report the main efforts employed to control this disease since the 1940s and the emergence of Plasmodium falciparum and Plasmodium vivax chemoresistanc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gama BE,Lacerda MV,Daniel-Ribeiro CT,Ferreira-da-Cruz Mde F

更新日期：2011-08-01 00:00:00

abstract：:It is generally accepted that Plasmodium vivax, the most widely distributed human malaria parasite, causes mild disease and that this species does not sequester in the deep capillaries of internal organs. Recent evidence, however, has demonstrated that there is severe disease, sometimes resulting in death, exclusively...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Costa FT,Lopes SC,Ferrer M,Leite JA,Martin-Jaular L,Bernabeu M,Nogueira PA,Mourão MP,Fernandez-Becerra C,Lacerda MV,del Portillo H

更新日期：2011-08-01 00:00:00

abstract：:Maternal malnutrition during the lactation period in early development may have long-term programming effects on adult offspring. We evaluated the combined effects of parasitological behaviour and histopathological features and malnutrition during lactation. Lactating mice and their pups were divided into a control gr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Corrêa CL,Lisboa PC,Oliveira Ed,Moura EG,Oliveira RM,Gomes AC,Machado-Silva JR

更新日期：2011-08-01 00:00:00

abstract：:In visceral leishmaniasis, phlebotomine vectors are targets for control measures. Understanding the ecosystem of the vectors is a prerequisite for creating these control measures. This study endeavours to delineate the suitable locations of Phlebotomus argentipes with relation to environmental characteristics between ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kesari S,Bhunia GS,Kumar V,Jeyaram A,Ranjan A,Das P

更新日期：2011-08-01 00:00:00

abstract：:The epidemiological features of rotavirus A (RVA) infection differ between children from developing and developed countries which could result in differences in vaccine efficacy around the world. To evaluate the impact of Rotarix™ on RVA prevalence, we monitored RVA genotypes circulating in Goiânia by monitoring virus...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Borges AM,Dias e Souza M,Fiaccadori FS,Cardoso Dd

更新日期：2011-06-01 00:00:00

abstract：:The nematode parasites of Rhinella marina include species of the genus Rhabdias (Rhabdiasidae: Rhabditoidea). The present study describes Rhabdias paraensis sp. nov., which parasitizes the lungs of R. marina in Brazilian Amazonia. Of the more than 70 known species of this genus, 18 are parasites of bufonids, of which,...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos JN,Melo FT,Nascimento Lde C,Nascimento DE,Giese EG,Furtado AP

更新日期：2011-06-01 00:00:00

abstract：:Benznidazole (Bz) exhibits toxic side effects in animal studies and clinical use. Reductive metabolism of Bz in liver microsomes modulates the duration of its chemotherapeutic effect and its toxicity. The rate of this metabolism depends on age and is less intense in newborns and youngsters than in adults. In the prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bulffer RF,Castro JA,Fanelli SL

更新日期：2011-05-01 00:00:00

abstract：:The schistosomal parasite plays a critical role in the development of malignant lesions in different organs. The pathogenesis of cancer is currently under intense investigation to identify reliable prognostic indices for disease detection. The objective of this paper is to evaluate certain biochemical parameters as di...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Hamed MA,Ahmed SA,Khaled HM

更新日期：2011-05-01 00:00:00

abstract：:Direct smear examination using Ziehl-Neelsen staining for pulmonary tuberculosis (PTB) diagnosis is inexpensive and easy to use, but has the major limitation of low sensitivity. Rapid molecular methods are becoming more widely available in centralized laboratories, but they depend on timely reporting of results and st...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Michelon CT,Rosso F,Schmid KB,Sperhacke RD,Oliveira MM,Kritski AL,Rezende L Jr,Costa ER,Ribeiro AW,Verza M,Cafrune PI,Silva MS,Kuhleis D,Zaha A,Rossetti ML

更新日期：2011-03-01 00:00:00

abstract：:Several protozoan parasites exist in the Trypanosomatidae family, including various agents of human diseases. Multiple lines of evidence suggest that important differences are present between the translational and mRNA processing (trans splicing) systems of trypanosomatids and other eukaryotes. In this context, certai...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva MT,Ambrósio DL,Trevelin CC,Watanabe TF,Laure HJ,Greene LJ,Rosa JC,Valentini SR,Cicarelli RM

更新日期：2011-03-01 00:00:00

abstract：:The global emergence and spread of malaria parasites resistant to antimalarial drugs is the major problem in malaria control. The genetic basis of the parasite's resistance to the antimalarial drug chloroquine (CQ) is well-documented, allowing for the analysis of field isolates of malaria parasites to address evolutio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sutar SK,Gupta B,Ranjit M,Kar SK,Das A

更新日期：2011-02-01 00:00:00

abstract：:The objective of this study was to evaluate the feeding behavior of Triatoma vitticeps through the identification of its food sources and the characterization of the blood ingestion process. In addition, we aimed to verify if the saliva of this vector interferes with the perception of the host during the feedings by c...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza Rde C,Soares AC,Alves CL,Lorosa ES,Pereira MH,Diotaiuti L

更新日期：2011-02-01 00:00:00

abstract：:Citral, the main constituent of lemongrass (Cymbopogon citratus) essential oil, was added to Trypanosoma cruzi cultures grown in TAU3AAG medium to observe the effect on the epimastigote-to-trypomastigote differentiation process (metacyclogenesis). Our results showed that citral (20 μg/mL) did not affect epimastigote v...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardoso J,Soares MJ

更新日期：2010-12-01 00:00:00

abstract：:Mosquito-borne diseases such as dengue fever, chikungunya or malaria affect millions of people each year and control solutions are urgently needed. An international research program is currently being developed that relies on the introduction of the bacterial endosymbiont Wolbachia pipientis into Aedes aegypti to cont...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Popovici J,Moreira LA,Poinsignon A,Iturbe-Ormaetxe I,McNaughton D,O'Neill SL

更新日期：2010-12-01 00:00:00

abstract：:The diagnosis of meningitic angiostrongyliasis (MA) is based on clinical criteria. A lumbar puncture is used as a diagnostic tool, but it is an invasive procedure. The blood eosinophil levels are also assessed and used in the diagnosis of this disease. We enrolled 47 patients with serologically proven MA and 131 contr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sawanyawisuth K,Sawanyawisuth K,Senthong V,Limpawattana P,Intapan PM,Tiamkao S,Jitpimolmard S,Chotmongkol V,Barrett-Connor E

更新日期：2010-11-01 00:00:00

abstract：:The presence of Anopheles (Nyssorhynchus) dunhami Causey in Colombia (Department of Amazonas) is confirmed for the first time through direct comparison of mtDNA cytochrome c oxidase I (COI) barcodes and nuclear rDNA second internal transcribed spacer (ITS2) sequences with topotypic specimens of An. dunhami from Tefé, ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ruiz F,Linton YM,Ponsonby DJ,Conn JE,Herrera M,Quiñones ML,Vélez ID,Wilkerson RC

更新日期：2010-11-01 00:00:00

abstract：:We present filaria-nested polymerase chain reaction (PCR), which is based on amplification of first internal transcribed spacer rDNA to distinguish three parasitic filarial species (Onchocerca volvulus, Mansonella ozzardi and Mansonella perstans) that can be found in the Amazon Region. Nested PCR-based identifications...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tang TH,López-Vélez R,Lanza M,Shelley AJ,Rubio JM,Luz SL

更新日期：2010-09-01 00:00:00

abstract：:This paper presents the morphological, histological and ultrastructural characteristics of Myxobolus oliveirai sp. nov., a parasite of the gill filaments in Brycon hilarii from the Brazilian Pantanal. Out of 216 B. hilariispecimens examined (126 wild and 90 cultivated), 38.1% of wild specimens (n = 48) were infected. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Milanin T,Eiras JC,Arana S,Maia AA,Alves AL,Silva MR,Carriero MM,Ceccarelli PS,Adriano EA

更新日期：2010-09-01 00:00:00

abstract：:Protection against Fasciola hepatica in goats immunized with a synthetic recombinant antigen from Schistosoma mansoni fatty acid-binding protein 14 (rSm14) was investigated by assessing worm burdens, serum levels of hepatic enzymes, faecal egg count and hepatic damage, which was evaluated using gross and microscopic m...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mendes RE,Zafra R,Pérez-Ecija RA,Buffoni L,Martínez-Moreno A,Tendler M,Pérez J

更新日期：2010-08-01 00:00:00

abstract：:Mycobacterium fortuitum is a rapidly growing nontuberculous Mycobacterium that can cause a range of diseases in humans. Complications from M. fortuitum infection have been associated with numerous surgical procedures. A protective immune response against pathogenic mycobacterial infections is dependent on the granulom...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva TR,Petersen AL,Santos Tde A,Almeida TF,Freitas LA,Veras PS

更新日期：2010-08-01 00:00:00

abstract：:In this transversal study, factors related to infection with and transmission of Schistosoma mansoni were explored. Based on stool examinations of two Kato-Katz smears of a single sample, the prevalences of schistosomiasis and geohelminths were established. In a multivariable analysis, sets of demographic, socio-econo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Enk MJ,Lima AC,Barros Hda S,Massara CL,Coelho PM,Schall VT

更新日期：2010-07-01 00:00:00